Airborne Transmission of Bordetella pertussis

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منابع مشابه

Transmission of Bordetella pertussis to young infants.

BACKGROUND Pertussis vaccination has reduced the number of notified cases in industrialized countries from peak years by more than 95%. The effect of recently recommended adult and adolescent vaccination strategies on infant pertussis depends, in part, on the proportion of infants infected by adults and adolescents. This proportion, however, remains unclear, because studies have not been able t...

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Airborne transmission of Bordetella pertussis demonstrated in a baboon model of whooping cough.

Pertussis is a vaccine-preventable respiratory disease caused by Bordetella pertussis [1]. Globally, it is estimated that pertussis vaccines prevented approximately 700 000 deaths in 2008, attesting to the ostensible success of the vaccines [2]. However, despite vaccine coverage approaching 90% [3], 16 million cases of pertussis occur annually [2], resulting in 195 000 deaths in children <5 yea...

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Regulation of pertussis toxin and lipopolysaccharide levels of Bordetella pertussis 134 in response to modulators

  Whooping cough (pertussis) is a highly contagious disease of the human respiratory tract, which is caused by Bordetella pertussis. Reemerge of pertussis in some highly immunized populations and divergency in gene order among several B. pertussis strains promoted this research to study the change of pertussis toxin (PT) and lipopolysacharide levels in response to the different environments. Th...

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Asymptomatic transmission and the resurgence of Bordetella pertussis

BACKGROUND The recent increase in whooping cough incidence (primarily caused by Bordetella pertussis) presents a challenge to both public health practitioners and scientists trying to understand the mechanisms behind its resurgence. Three main hypotheses have been proposed to explain the resurgence: 1) waning of protective immunity from vaccination or natural infection over time, 2) evolution o...

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Transmission of Bordetella holmesii during Pertussis Outbreak, Japan

We describe the epidemiology of a pertussis outbreak in Japan in 2010-2011 and Bordetella holmesii transmission. Six patients were infected; 4 patients were students and a teacher at the same junior high school. Epidemiologic links were found between 5 patients. B. holmesii may have been transmitted from person to person.

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ژورنال

عنوان ژورنال: Journal of Infectious Diseases

سال: 2012

ISSN: 0022-1899,1537-6613

DOI: 10.1093/infdis/jis443